Supplementary Figure 3: Genes in the 1p31 locus region. | Nature Genetics

Supplementary Figure 3: Genes in the 1p31 locus region.

From: Severe osteoarthritis of the hand associates with common variants within the ALDH1A2 gene and with rare variants at 1p31

Supplementary Figure 3

Locations of genes in the region on 1p31 that is shared by all the affected carriers and the locations of the three associated markers and the LD blocks are shown. The genes are LINC00466 (long intergenic non-protein-coding RNA 466), FOXD3 (forkhead box D3), ALG6 (α-1,3-glucosyltransferase), ITGB3BP (integrin β3–binding protein), EFCAB7 (EF-hand calcium-binding domain 7), PGM1 (phosphoglucomutase 1) and ROR1 (receptor tyrosine kinase–like orphan receptor 1), and the pseudogene is DLEU2L (deleted in lymphocytic leukemia 2-like). All positions are in NCBI Build 36 coordinates. The plot was created using a stand-alone version of LocusZoom software35 (http://csg.sph.umich.edu/locuszoom/).

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