Supplementary Figure 8: Examples of autosomal structural genetic aberrations of ≥ 2 Mb in length in the ULSAM cohort.

LRR and BAF values from SNP array data as well as validation with next-generation sequencing using low-coverage whole-genome sequencing (panel c) or exome sequencing (panels a,b,d–f) with an average coverage of 17×. Triangles indicate the positions of calls for structural variants, and probes within these positions are plotted in red. Panels c and d show two examples of CNNLOH; in these cases, next-generation sequencing did not, as expected, detect any structural changes in these regions.