Supplementary Figure 10: Example of visual inspection of cluster plots for SNPs that demonstrated evidence of association in the first stage (RADIOGEN cohort).

SNP cluster priors (red, blue and green dashed-line cluster boundaries as defined by Affymetrix training data indicating the prior localization of the genotype clusters) and SNP cluster posteriors (solid-line cluster boundaries as defined by experimental data combining information from priors) are shown. The gray and pink dashed line indicates the localization (log radio, x axis) of the prior for each allele (noted by Affymetrix as A or B). The final genotype for each sample is indicated by red triangles (homozygous for allele A), blue squares (heterozygous samples) and green circles (homozygous for allele B).