Supplementary Figure 8: Histograms of standardized total average toxicity (STAT) scores and residuals (R-STAT). | Nature Genetics

Supplementary Figure 8: Histograms of standardized total average toxicity (STAT) scores and residuals (R-STAT).

From: A three-stage genome-wide association study identifies a susceptibility locus for late radiotherapy toxicity at 2q24.1

Supplementary Figure 8

(a−e) Frequency distributions of STAT score on the RADIOGEN (a,b), RAPPER (c,d) and Gene-PARE (e) cohorts. (f−i) Frequency distributions of R-STAT score on the RADIOGEN (f,g) and RAPPER (h,i) cohorts, which approximately follow a normal distribution. There are no R-STAT data for the Gene-PARE cohort because no associated covariates were identified in this cohort. Light blue refers to overall acute toxicity, while dark blue refers to overall late toxicity. The dashed line shows the threshold of 1 s.d. after the median used to dichotomize the variable.

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