Supplementary Figure 6: Extended gallery of TEM images of centrioles in C2cd3-mutant and control cells.
From: The oral-facial-digital syndrome gene C2CD3 encodes a positive regulator of centriole elongation
(a) Longitudinal TEM sections of C2cd3Gt/+ and C2cd3Hty/Hty centrioles. Centrioles from the mutant MEFs appear stunted and lack all appendages (arrows point to subdistal appendages; arrowheads point to distal appendages). Scale bar, 100 nm. (b) Serial transverse TEM sections of C2cd3Gt/+ and C2cd3Hty/Hty centrioles. C2cd3Gt/+ centrioles are contained within 5 to 6 sections, whereas C2cd3Hty/Hty centrioles span fewer than 3 sections. Scale bar, 100 nm.
