Supplementary Figure 5: QQ plots of observed versus expected P values for the NCI study based on a logistic regression model adjusted for age, sex and the first study-specific eigenvector to adjust for population stratification.

The red dots represent a plot using all SNPs, whereas the green dots represent a plot excluding SNPs (and SNPs within 500 kb of SNPs) previously reported to be associated with ESCC risk. The inflation factor λ for the plot using all SNPs was 1.01.