Supplementary Figure 1: Maturation arrest in bone marrow smears from a JAGN1-deficient patient (P4).
From: JAGN1 deficiency causes aberrant myeloid cell homeostasis and congenital neutropenia
JAGN1-deficient patients in this study showed (sometimes intermittently, as in this figure) signs of maturation arrest at the promyelocyte/myelocyte stage, a hallmark feature of classical severe congenital neutropenia.
