Supplementary Figure 4: Association results for genotyped SNPs at the discovery stage.
From: Common variants near ABCA1 and in PMM2 are associated with primary open-angle glaucoma
The genome-wide distribution of −log10 P values from the unadjusted Cochran-Armitage trend test is shown across the chromosomes. Values are shown for 870,261 SNPs that were of sufficient quality, after quality control filtering, in 966 unrelated Han Chinese cases with HPG and in 1,005 unrelated Han Chinese controls, after genetic matching and correction for the inflation factor of 1.016. Each chromosome is depicted in a different color. −log10 (UNADJ), the −log10 P value of the Cochran-Armitage trend test, was not adjusted for multiple testing.
