Supplementary Figure 2: Comparison of survival curves and the location of tumors. | Nature Genetics

Supplementary Figure 2: Comparison of survival curves and the location of tumors.

From: Transposon mutagenesis identifies genes and evolutionary forces driving gastrointestinal tract tumor progression

Supplementary Figure 2

SB mutagenesis shortened the lifespan of (a) ApcMin, (b) KrasG12D, (c) Smad4KO and (d) wt mice but not p53R172H mice (e). Polyps developed mainly in the duodenum and jejunum. (f) The polyp number in the colon was significantly higher in the KrasG12D cohort compared to the Smad4KO and p53R172H cohorts (t test, P < 0.05). Duo, duodenum; Jej, jejunum; Ile, ileum; Col, colon.

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