Supplementary Figure 5: Voltage dependence of S325Y and V356L KCNH1 channel activation.
From: Mutations in KCNH1 and ATP6V1B2 cause Zimmermann-Laband syndrome
(a,b) Mean values (±s.e.m.) of normalized current amplitudes (a) and whole-cell conductance (b) for S325Y (n = 14) and V356L (n = 11). Data points in a are connected by lines; the dark gray lines in b represent fits to the data points using equation (2). Corresponding data for the double mutant S325Y/V356L and for wild-type (WT) channels are shown for comparison as light gray and black lines, respectively (data from Fig. 4). Fit parameters are given in Supplementary Table 4.
