Supplementary Figure 4: Numbers and separation distances of promoter interactions.
From: Mapping long-range promoter contacts in human cells with high-resolution capture Hi-C
(a) Notch plot displaying the separation distances between active and inactive promoters in CD34+ cells and their interacting fragments. P values were derived by pairwise t test (Holm adjusted). (b) The separation distances of the interactions between two baited promoter fragments. (c) The interaction profiles up- and downstream of active and inactive promoters in CD34+ cells. The insets display a zoomed-in view of the interactions that are within 40 kb of the promoter, with light shading representing the 95% confidence interval. (d) The propensity of promoter interactions for the gene body relative to equally sized upstream sequences for active (red) and inactive (blue) genes. (e) Notch plot of the number of interactions of baited promoters in CD34+ cells with non-baited interacting fragments. P values were derived by pairwise t test (Holm adjusted). (f) Number of interactions of non-baited interacting fragments in CD34+ cells to baited promoters.
