Supplementary Figure 9: Functional activity of promoter-interacting fragments by luciferase assay.
From: Mapping long-range promoter contacts in human cells with high-resolution capture Hi-C
(a) The enhancer activity of interacting fragments that interact with active genes, relative to a minimal promoter plasmid. (b) The silencing activity of a fragment that interacts with the inactive BCL6 promoter, relative to a constitutively active promoter plasmid. Relative luciferase activity is displayed as the mean, with standard error of three independent experiments, each carried out with technical triplicates. Statistical significance was determined by t test (one-tailed).
