Supplementary Figure 1: Comparisons of Hi-C and CHi-C libraries.
From: Mapping long-range promoter contacts in human cells with high-resolution capture Hi-C
(a) Symmetric genome-wide contact matrix (log2 read count) from 45 million reads (chr. 1–chr. Y). Reads were grouped into 1-Mb bins. Chr. 1 is shown as a chromosome-wide example. (b) Distribution of di-tag read separation distances in cis, in Hi-C and CHi-C libraries from GM12878 and CD34+ cells. (c) Heat map of di-tag reads exhibiting conserved topological domain structure in Hi-C and CHi-C libraries. Reads were grouped into 40-kb bins. (d) Number of unique reads in Hi-C and CHi-C samples mapping to bait and non-bait fragments. The red dot denotes the mean.
