Supplementary Figure 13: Regional plot and conditional analysis at the reported MUC1 locus at 1q22 that replicates in Iceland.
From: Loss-of-function variants in ATM confer risk of gastric cancer
The vertical dashed line indicates the missense variant rs760077[A] in MTX1 (P = 1.1 × 10−9, OR = 0.79, AF = 35.1%, p.Thr63Ser). The horizontal dashed line shows the P-value threshold for the locus. Black circles correspond to unadjusted P values; red crosses correspond to P values adjusted for rs760077. The associations are based on 2,500 gastric cancer patients and 205,652 controls (GC all).
