Supplementary Figure 4: A2ML1 has very faint or almost absent immunolocalization to the cochlea. | Nature Genetics

Supplementary Figure 4: A2ML1 has very faint or almost absent immunolocalization to the cochlea.

From: Rare A2ML1 variants confer susceptibility to otitis media

Supplementary Figure 4

Whole-mount cochleae of P7 C57BL/6J mice immunolabeled with A2ML1 (green) showed very low or background levels of expression in the basal coil of the organ of Corti (OC). This very low or negative OC staining is consistent with no detectable mRNA expression for A2ML1 within the Shared Harvard Inner-Ear Laboratory Database. Actin (red) and nuclei/DAPI (blue) labeling were used to highlight the OC structure. Scale bar, 10 μm.

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