Supplementary Figure 7: Enrichment in chromatin state and noncoding RNA elements. | Nature Genetics

Supplementary Figure 7: Enrichment in chromatin state and noncoding RNA elements.

From: Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci

Supplementary Figure 7

Variants in regulatory enhancer, promoter and insulator elements from 12 cell types and noncoding RNA elements from 25 cell types were tested for enrichment of average posterior causal probability compared to variants in shifted elements. Variants in islet enhancer elements demonstrated significant enrichment (fold = 1.97; P = 0.00022), and variants in islet and HepG2 promoter elements demonstrated nominally significant enrichment (P < 0.01).

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