Supplementary Figure 6: Representative GSEA plots.
From: Recurrent mTORC1-activating RRAGC mutations in follicular lymphoma
GSEA of gene expression data derived from RNA-seq of five RRAGC-mutated versus eight RRAGC–wild type cases. This showed significant enrichment for gene sets in several processes involved in translation and cell cycle regulation, which were upregulated in the RRAGC-mutated tumors as compared to wild-type tumors. Hits displayed below the graph show where the members of the gene set appear in the ranked list of genes. FDR q values and further gene sets are fully listed in Supplementary Table 10.
