Supplementary Figure 3: Copy number of RRAGC as compared to other gene loci.
From: Recurrent mTORC1-activating RRAGC mutations in follicular lymphoma
The top panel shows the log R values for each of the gene loci indicated from all 24 samples from the five WES cases, and the bottom panel shows the log R values from our previously published SNP6.0 data set comprising 29 different follicular lymphoma samples and corresponding paired transformed follicular lymphoma. The gene locus for TNFRSF14, 1p36.32, was chosen as a reference locus as it is commonly subject to frequent copy number deletions in follicular lymphoma. The horizontal dashed line indicates the log R value of −0.2, with values below this measure indicative of deletions and those above 0.2 indicative of gains, as reported previously3.
