Supplementary Figure 1: QQ plots for individual data sets meta-analyzed in NEIGHBORHOOD and the NEIGHBORHOOD meta-analysis. | Nature Genetics

Supplementary Figure 1: QQ plots for individual data sets meta-analyzed in NEIGHBORHOOD and the NEIGHBORHOOD meta-analysis.

From: Genome-wide association analysis identifies TXNRD2, ATXN2 and FOXC1 as susceptibility loci for primary open-angle glaucoma

Supplementary Figure 1

The top eight panels are QQ plots for individual data sets; the bottom panel is for the NEIGHBORHOOD meta-analysis. NEIGHBORHOOD, National Eye Institute Glaucoma Human Genetics Collaboration Heritable Overall Operational Database; NHS/HPFS, Nurses Health Study/Health Professionals Follow-up Study; MEEI, Massachusetts Eye and Ear Infirmary; NEIGHBOR, National Eye Institute Glaucoma Human Genetics Collaboration; OHTS, Ocular Hypertension Treatment Study; WGHS, Women’s Genome Health Study. Individual λ values are: NHS/HPFS Affymetrix, 1.008; NHS/HPFS Illumina, 1.024; Iowa, 1.031; Marshfield, 1.003; MEEI, 1.007; NEIGHBOR, 1.051; OHTS, 1.015; WGHS, 1.011. The overall NEIGHBORHOOD λ value is 1.064.

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