Figure 3: The parasitic female, free-living female and iL3 transcriptomes of Strongyloides species.
From: The genomic basis of parasitism in the Strongyloides clade of nematodes
The progeny of the parasitic female pass out of the host (as larvae for S. stercoralis or as eggs and larvae for S. ratti), where iL3s can develop directly or free-living males and females develop whose progeny develop into iL3s; iL3s then infect hosts. The parasite of humans S. stercoralis can undergo internal autoinfection (gray dashed line) where iL3s develop and internally reinfect the same host. The transcriptome of the parasitic female, free-living female and iL3 were compared for S. ratti and S. stercoralis. Representative GO terms that were significantly enriched (left side of the box) and Ensembl Compara gene families significantly upregulated (right side of the box) for each of these three stages of the life cycle are summarized. The pie charts show the proportion of the GO terms common to S. ratti and S. stercoralis or unique to each species. Numbers on the right in the boxes represent the number of genes upregulated in each gene family for S. ratti and S. stercoralis. MF, molecular function; BP, biological process; CC, cellular component.
