Supplementary Figure 8: Myc-tagged NUP93 interacts with GFP-tagged SMAD4 upon co-overexpression in HEK293 cells.
From: Mutations in nuclear pore genes NUP93, NUP205 and XPO5 cause steroid-resistant nephrotic syndrome
Clones reflecting the C-terminal mutations identified in individuals with steroid-resistant nephrotic syndrome (Lys442Asn_fs*14, Gly591Val, Tyr629Cys) abrogate the interaction.
