Supplementary Figure 3: Renal histologies of individuals A2403, A3256 and A1394 with recessive mutations in NUP93. | Nature Genetics

Supplementary Figure 3: Renal histologies of individuals A2403, A3256 and A1394 with recessive mutations in NUP93.

From: Mutations in nuclear pore genes NUP93, NUP205 and XPO5 cause steroid-resistant nephrotic syndrome

Supplementary Figure 3

(a) H&E staining at high magnification (63×) shows diffuse mesangial sclerosis in A2403-21 and focal-segmental glomerulosclerosis in A3256-21 and A1394-21. (b) H&E staining at low magnification (40×) shows tubular atrophy, tubular dilation with protein casts and cysts with interstitial infiltrations. (c) Transmission electron microscopy images show partial foot process effacement (arrowheads) (15,000× magnification). N/D, no data. Scale bars: 30 μm (a,b) and 2 μm (c).

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