Supplementary Figure 2: Prioritizing genes at the NMRAL1 locus for schizophrenia. | Nature Genetics

Supplementary Figure 2: Prioritizing genes at the NMRAL1 locus for schizophrenia.

From: Integration of summary data from GWAS and eQTL studies predicts complex trait gene targets

Supplementary Figure 2

(a) Top, P values from the GWAS for schizophrenia1 (brown dots) and P values from SMR tests (diamonds) using Westra eQTL data2. Bottom, P values from the Westra and Ramasamy eQTL studies3 for NMRALI1. Shown in a are all the SNPs available in the GWAS and eQTL data. (b,c) Effect sizes of the SNPs (used for the HEIDI test) from the GWAS against those from the Westra and Ramasamy eQTL studies. The orange dashed lines represent the estimate of bxy at the top cis-eQTL (rather than the regression line). Error bars are the standard errors of SNP effects.

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