Supplementary Figure 6: Inbreeding coefficients from Dutch whole-genome sequencing cohort.
From: NEK1 variants confer susceptibility to amyotrophic lateral sclerosis
Four ALS patients sampled from an isolated community in the Netherlands can be seen to exhibit elevated coefficients of inbreeding (shown in red) relative to a larger panel of Dutch genome sequences (n = 1,861). Box plots show cohort median, interquartile range, 2.5% quantile and 97.5% quantile.
