Supplementary Figure 9: ERG transcriptional levels and intron retention in DUX4/ERG cases.
From: Deregulation of DUX4 and ERG in acute lymphoblastic leukemia
RNA–seq coverage (y axis) in the genomic region encoding ERG exons 5–10 (RefSeq accession NM_182918) for three tumors with ERG alt expression (top) and three tumors without ERG alt expression (bottom). The location of the ERGalt exon is marked in red and indicated by an arrow. Samples appended with an asterisk (e.g., SJERG016 above and SJERG031 below) are those that harbor ERG focal deletion. Aberrant expression of intron 6 is higher in ERGalt-negative samples (bottom) than in ERGalt-positive samples (top).
