Supplementary Figure 2: Design of the study, investigated phenotypes, sources of data and sample size.

The reported sample size is the maximum available for a given trait or set of traits in this study. *In the study by Knowles and colleagues (PubMed ID: 25798622), insulin sensitivity was measured by euglycemic clamp or insulin suppression test in 2,764 European individuals from four cohorts. IR, insulin resistance; FIadjBMI, fasting insulin levels adjusted for body mass index; TG, triglyceride levels; HDL, high-density lipoprotein cholesterol levels; ISI, insulin sensitivity index; DEXA, dual-energy X-ray absorptiometry; BF%, body fat percentage; FPLD1, familial partial lipodystrophy type 1; MAGIC, Meta-Analyses of Glucose- and Insulin-related traits Consortium; GLGC, Global Lipids Genetics Consortium; GIANT, Genetic Investigation of ANthropometric Traits; DIAGRAM, DIAbetes Genetics Replication And Meta-analysis; CARDIOGRAM, Coronary ARtery DIsease Genome-wide Replication and Meta-analysis; C4D, Coronary Artery Disease Genetics consortium.