Supplementary Figure 11: Percentage of nodes where resistance to other drugs arose prior or coincident with an Xpert MTB/RIF-detectable mutation.

(a) Resistance to single drugs. (b) Resistance to multiple drugs. This figure shows results for cases where all nodes between the first and last drug acquisition event leading up to the Xpert MTB/RIF-detectable mutation fit our filtering criteria (>90% bootstrap in the more ancestral node of a pair; maximal branch lengths between pairs <1 × 10–4).