Supplementary Figure 4: Phenotypic distributions in segregants with a varying number of growth-decreasing alleles at the radial loci across the six loci in 14 epistatic networks affecting growth in different media. | Nature Genetics

Supplementary Figure 4: Phenotypic distributions in segregants with a varying number of growth-decreasing alleles at the radial loci across the six loci in 14 epistatic networks affecting growth in different media.

From: Accounting for genetic interactions improves modeling of individual quantitative trait phenotypes in yeast

Supplementary Figure 4

The networks are divided depending on whether the hub QTL is a significant capacitor or not. Each Tukey box plot (the bottom/top of the box are the first/third quartiles, the band is the median and the whiskers extend to the lowest/highest data point within 1.5 times the interquartile range) represents a group of segregants that share the same number of growth-decreasing alleles at the five radial QTLs in the respective networks. The segregants are divided and colored based on the genotype at the hub QTL (green/gray boxes for BY/RM alleles, respectively). The x axis gives the number of growth-decreasing alleles at the radial QTLs and the number of segregants in each group. The regression lines illustrate the fit of linear additive models to segregants with alternative genotypes at the hub QTL.

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