Supplementary Figure 6: Association of shet estimates with PubMed gene score.
From: Estimating the selective effects of heterozygous protein-truncating variants from human exome data
[a] The average PubMed gene score is calculated by shet decile. Estimates of selection (shet) are positively correlated with the average PubMed gene score. Each bin contains 10% of all covered genes, ordered from greatest to smallest shet values, in bins 1 through 10, respectively. [b] The PubMed gene score is significantly positively correlated with the (p<0.0001) using a logarithmic model (y=4.557*log(shet)+44.449) with R2=0.00409.
