Supplementary Figure 3: Association of shetQUOTE shet estimates with known disease genes.
From: Estimating the selective effects of heterozygous protein-truncating variants from human exome data
Proportion of genes listed to have a disease association in the Human Gene Mutation Database, and number of disease associations related to each gene in OMIM MorbidMap, in each shet decile. Each bin is expected to contain 10% of all covered genes, ordered from greatest to smallest shet values, in bins 1 through 10, respectively.
