Supplementary Figure 1: Association between IFNL4 rs368234815, IFNL3 rs4803217, and IFNL4 rs117648444 genotype and serum sCD163 in 506 patients with chronic hepatitis C virus. | Nature Genetics

Supplementary Figure 1: Association between IFNL4 rs368234815, IFNL3 rs4803217, and IFNL4 rs117648444 genotype and serum sCD163 in 506 patients with chronic hepatitis C virus.

From: IFN-λ3, not IFN-λ4, likely mediates IFNL3–IFNL4 haplotype–dependent hepatic inflammation and fibrosis

Supplementary Figure 1

(a–c) The x axis shows genotype at rs368234815 using the dominant model of inheritance (TT = 223, TΔG/ΔGΔG = 283) (a), genotype at rs4803217 using the dominant model of inheritance (TT = 232, TG/GG = 274) (b), and genotype at rs117648444 (GG = 423, GA/AA = 83) (c). The y axis shows sCD163 expression level (mg/ml) by ELISA. The number of independent samples tested in each group is shown. Each group is represented as a box plot, and the median values are shown as thick dark horizontal lines. The box covers the 25th to 75th percentiles. We tested the difference in the median values between genotypes using two-tailed Mann–Whitney tests. We plotted the box plots using GraphPad Prism 7.

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