Supplementary Figure 2: Regional chromatin state plots for SNPs with P < 5 × 10−8 in four genomic loci. | Nature Genetics

Supplementary Figure 2: Regional chromatin state plots for SNPs with P < 5 × 10−8 in four genomic loci.

From: Genome-wide association meta-analysis of 78,308 individuals identifies new loci and genes influencing human intelligence

Supplementary Figure 2

(a–d) Chromatin state plots are included for 4 of the 18 genome-wide significant loci. The 1p31.1 and 20q13.13 loci are not included because the lead SNPs in these regions (rs66495454 and rs113315451) are indels. In each picture, the top panel shows the lead SNP (purple) and all other SNPs reaching genome-wide significance in the region. The colors represent r2 with the lead SNP. The bottom panel shows chromatin states for 127 tissue types (y axis) across the whole region. Different colors represent the different states, varying from “active TSS” (state 1) to “quiescent/low” (state 15). This information can be used to determine which SNPs to study in a functional follow-up.

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