Supplementary Figure 3: Risk allele effect estimates in the literature and in UK Biobank for a set of previously reported CAD variants.

Plot of the effect estimates for 56 CAD-associated DNA sequence variants as reported in the 1000G-imputed CARDIoGRAMplusC4D analysis1 and in our UK Biobank GWAS analysis. β = 0.92, 95% CI = 0.77–1.06; P = 1.8 × 10−17.