Supplementary Figure 13: Saturation analysis of called H3K27ac peaks stratified by T2E status suggests we have identified at least 95% of potential peaks. | Nature Genetics

Supplementary Figure 13: Saturation analysis of called H3K27ac peaks stratified by T2E status suggests we have identified at least 95% of potential peaks.

From: TMPRSS2–ERG fusion co-opts master transcription factors and activates NOTCH signaling in primary prostate cancer

Supplementary Figure 13

A non-linear regression model was fit to the number of new peaks obtained sequentially over all samples for 1,000 permutations of sample orders and stratified according to (a) T2E and (b) nonT2E status. Individual points show mean new peaks per sample added and associated standard error of the mean fitted blue line shows fitted model with saturation line (red) marked as well as estimated number of samples needed to identify 95, 97 and 99% of peaks (grey lines).

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