Supplementary Figure 6: Enhancer deletions result in delayed skull ossification and reduced bone length. | Nature Genetics

Supplementary Figure 6: Enhancer deletions result in delayed skull ossification and reduced bone length.

From: Composition and dosage of a multipartite enhancer cluster control developmental expression of Ihh (Indian hedgehog)

Supplementary Figure 6

Left, μCT scan of wild-type mouse forelimb and skull displaying the different regions used for measurement. Right, bone measurements for Del(4–6) and Del(7–9) mutants and wild-type age-matched controls (P70). Note the reduction in ulna and nasal suture length for Del(4–6). Del(4–6) shows a more severe effect on digit length than that observed in Del(7–9) mutants. Bars represent the mean of n = 3 different individuals (circles). Two-sided Student's t test, *P < 0.05; **P < 0.01; ***P < 0.001; ****P < 0.0001; ns, not significant.

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