Supplementary Figure 3: Transgenic reporter assay (LacZ) of elements positive at E17.5. | Nature Genetics

Supplementary Figure 3: Transgenic reporter assay (LacZ) of elements positive at E17.5.

From: Composition and dosage of a multipartite enhancer cluster control developmental expression of Ihh (Indian hedgehog)

Supplementary Figure 3

Each element displays a lateral view of the embryo at E14.5 (scale bar, 2,000 μm), a dorsal view of the forelimbs (scale bar, 1,000 μm) and a top view of the skull at 17.5 (scale bar, 2,000 μm) together with tissue specificity scoring (bottom). All tested elements appear positive at E17.5 but not at E14.5 and are marked in Figure 1 in gray. An arrowhead indicates positive staining in the skull. The regulatory activity of the region as indicated by the inserted lacZ reporter (SB; black outline) is also displayed.

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