Supplementary Figure 10: Promoter occupancy of BAF complexes correlates with gene expression. | Nature Genetics

Supplementary Figure 10: Promoter occupancy of BAF complexes correlates with gene expression.

From: SMARCB1 is required for widespread BAF complex–mediated activation of enhancers and bivalent promoters

Supplementary Figure 10

(a-h) Expression analysis of (a) BRG1, (b) BAF155, (c) SS18, (d) BAF200, (e) H3K4me3, (f) H3K27ac, (g) H3K27me3, (h) SUZ12 over promoters in (top) empty and (bottom) BAF47 conditions. Promoters are binned by expression quintile or non-expressed genes (RPKM < 1). (i) Distribution of promoter categorization for all TTC1240 promoters. (j) Example tracks of H3K4me3-marked, H3K27me3-marked, and bivalent promoters in TTC1240 cells. (k) Distribution of promoter categorization for all G401 promoters. (l) Heatmap of H3K4me3, BRG1, H3K27ac, H3K27me3, and SUZ12 across all hg19 promoters in G401, ranked by H3K4me3 occupancy.

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