Supplementary Figure 13: BAF complex opposition of polycomb-mediated repression is limited in BAF47-insensitive EpS cell lines. | Nature Genetics

Supplementary Figure 13: BAF complex opposition of polycomb-mediated repression is limited in BAF47-insensitive EpS cell lines.

From: SMARCB1 is required for widespread BAF complex–mediated activation of enhancers and bivalent promoters

Supplementary Figure 13

(a) Heatmaps of H3K4me3, BRG1, H3K27ac, H3K27me3, and SUZ12 across all hg19 promoters in HS-ES-2M EpS cells, ranked by H3K4me3 occupancy. (b) Breakdown of promoter categorization for all HS-ES-2M promoters. (c) Metagene plots for BRG1, H3K27me3, and Input over all HS-ES-2M+BAF47 BRG1-BAF155 sites. (d) Heatmap of H3K4me3, BRG1, H3K27ac, H3K27me3, and SUZ12 across all hg19 promoters in VA-ES-BJ, ranked by H3K4me3 occupancy. (e) Breakdown of promoter categorization for all VA-ES-BJ promoters. (f) Metagene plots for BRG1, H3K27me3, and Input over all VA-ES-BJ+BAF47 BRG1 sites.

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