Supplementary Figure 2: H3K27ac HiChIP achieves high chromatin loop signal over background at low cell inputs. | Nature Genetics

Supplementary Figure 2: H3K27ac HiChIP achieves high chromatin loop signal over background at low cell inputs.

From: Enhancer connectome in primary human cells identifies target genes of disease-associated DNA elements

Supplementary Figure 2

(a) KR balanced interaction matrices focused around the Etv5 locus in mES cells with decreasing cellular starting material. (b) Read support reproducibility of loops in H3K27ac HiChIP libraries from 25 million cells as compared to HiChIP in lower cell input libraries. (c) Aggregate peak analysis of loops in mES H3K27ac HiChIP libraries.

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