Supplementary Figure 3: H3K27ac HiChIP generates reproducible chromatin loop signals at low cell inputs. | Nature Genetics

Supplementary Figure 3: H3K27ac HiChIP generates reproducible chromatin loop signals at low cell inputs.

From: Enhancer connectome in primary human cells identifies target genes of disease-associated DNA elements

Supplementary Figure 3

(a) Comparison of KR balanced interaction maps in H3K27ac HiChIP biological replicates. Each replicate corresponds to one side of the interaction map, separated by the diagonal. (b) Read support reproducibility of loops between H3K27ac HiChIP biological replicates. (c) HiCCUPS loop call overlap between H3K27ac HiChIP libraries from 25 million and 50,000 mES cells. (d) Preseq library complexity estimation of H3K27ac HiChIP libraries from 25 million and 50,000 mES cells.

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