Supplementary Figure 6: CERES preserves known cancer-specific genetic dependencies. | Nature Genetics

Supplementary Figure 6: CERES preserves known cancer-specific genetic dependencies.

From: Computational correction of copy number effect improves specificity of CRISPR–Cas9 essentiality screens in cancer cells

Supplementary Figure 6

(a-d) Known cancer-specific genetic dependencies are plotted against copy number before (left) and after (right) CERES correction for 342 cell lines. The dependencies plotted are: KRAS dependency colored by KRAS mutation status (a), BRAF dependency colored by BRAF mutation status (b), PIK3CA dependency colored by PIK3CA mutation status (c), and MYCN dependency with neuroblastoma cell lines in purple (d).

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