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A 'GEM' of a cell

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A third population of human T lymphocytes that express αβ T cell antigen receptors with restricted α-chain diversity has been identified. These cells recognize the lipid glucose monomycolate from Mycobacterium tuberculosis presented by CD1b.

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Figure 1: Comparison of T cell populations with a limited α-chain diversity.

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Correspondence to Mitchell Kronenberg.

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The authors declare no competing financial interests.

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Kronenberg, M., Zajonc, D. A 'GEM' of a cell. Nat Immunol 14, 694–695 (2013). https://doi.org/10.1038/ni.2644

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