Supplementary Figure 7: Functional comparison of IRF3, IRF7 and ELF4.
From: ELF4 is critical for induction of type I interferon and the host antiviral response
(a) Expression profile of IRF3, IRF7 and ELF4 in mouse analyzed by qRT-PCR(normalized by β-actin). Data were pooled from 3 independent experiments. There are 2 technical replicates within each experiment. (b&c) Peritoneal macrophages from Wild-type(WT), Elf4-/- or Irf3-/- were treated with LPS, infected with VSV or HSV-1. QRT-PCR measured the abundance of IFNβ (H) or ISG15 (I). *P<0.05 and **P<0.01 as determined by Student's t-test. Data were pooled from 3 independent experiments. There are 2 technical replicates within each experiment.
