Supplementary Figure 1: Effect of Hla on bacterial infection parameters.
From: Perivascular macrophages mediate neutrophil recruitment during bacterial skin infection
(a) Clinical manifestations, (b) Ear thickness, (c) RBC count following infection of C57BL/6 mice with S. aureus (WT or ΔHla) at various time points. (d) Ear swelling response and (e) RBC count of concomitant injection of purified Hla together with S. aureus (ΔHla) 12h p.i. (f) Neutrophil myeloperoxidase activity in back skin of mice infected with S. aureus (WT or ΔHla) at 12h p.i. MPO activity was normalized to tissue weight. (g) Neutrophil influx into ears infected with S. aureus strain USA300 in the presence or absence of anti-Hla serum. Bars represent mean±SD. Student's two-tailed unpaired t-test was used to determine the P-value. Data are representative of at least two independent experiments. Error bars indicate SD. **P<0.01; ***P<0.001.
