Figure 2: Concentration of IgE and IgG1 in serum from B cell–deficient μMT recipient mice infected with N. brasiliensis after adoptive transfer of purified memory B cells (1.4 × 104 per mouse; gated as B220+IgD−GL7−CD38+ memory B cells and the IgG1 and GFP combinations in Fig. 1b) and T cells from N. brasiliensis–infected mice, plus carrier splenocytes from mice deficient in recombination-activating gene 2 (a and b are two different experiments). | Nature Immunology

Figure 2: Concentration of IgE and IgG1 in serum from B cell–deficient μMT recipient mice infected with N. brasiliensis after adoptive transfer of purified memory B cells (1.4 × 104 per mouse; gated as B220+IgD−GL7−CD38+ memory B cells and the IgG1 and GFP combinations in Fig. 1b) and T cells from N. brasiliensis–infected mice, plus carrier splenocytes from mice deficient in recombination-activating gene 2 (a and b are two different experiments).

From: Addendum: IgE+ memory B cells and plasma cells generated through a germinal-center pathway

Figure 2

*P < 0.01, versus IgG1+GFP− cells (for IgE) or IgG1−GFPhi cells (for IgG1) (Dunnett's test). Data are representative of two independent experiments with two mice per group (IgG1+GFPhi and IgG1−GFPhi memory B cells) or two to three mice per group (IgG1+GFP− memory B cells) (mean ± s.e.m.).

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