Supplementary Figure 4: ATF3 does not bind the promoters of control genes but is induced by HDL in a model of atherosclerosis. | Nature Immunology

Supplementary Figure 4: ATF3 does not bind the promoters of control genes but is induced by HDL in a model of atherosclerosis.

From: High-density lipoprotein mediates anti-inflammatory reprogramming of macrophages via the transcriptional regulator ATF3

Supplementary Figure 4

a, Genomic loci of Il18 and Il13 with ChIP-Seq signals for ATF3 binding under the various stimulation conditions. b, qPCR analysis of ATF3 mRNA expression in Kupffer cells or hepatocytes isolated from Apoe-deficient mice fed on a Western diet and injected i.v. with PBS or HDL (100 mg/kg) (n=5 per group). a, Data was obtained from 3 biological replicates. b, Data are shown as the mean ±S.E.M, PBS versus HDL injected mice **p<0.01.

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