Supplementary Figure 6: Pathways associated with antibody response. | Nature Immunology

Supplementary Figure 6: Pathways associated with antibody response.

From: Molecular signatures of antibody responses derived from a systems biology study of five human vaccines

Supplementary Figure 6

Selected pathways from NCI-Nature Pathway Interaction Database whose expression at (a) day 3 or (b) day 7 post-vaccination was significantly (p < 0.01) correlated to antibody response. Genes are ranked according to Pearson correlation to antibody response, and the significance of pathways is tested by GSEA (see Method for details). Influenza LAIV is excluded here because this vaccine does not induce serum/plasma antibody responses. MCV4 has two sets of antibody correlation data: one against meningococcal polysaccharide (MCV4-PS) and another against diphtheria toxoid (MCV4-DT).

Back to article page