Supplementary Figure 12: Distinctive early transcription programs correlated to vaccine antibody response.

(a) Clustering analysis from Supplementary Figure 10b, marked by the three programs: Primary viral response (b), Polysaccharide response (c) and Protein recall response (d). From each data set in (a), the top 20 modules with highest positive correlations and the top 20 modules with highest negative correlations were selected. Among these selected modules, the modules concordant between two datasets (Pearson correlation coefficient above 0.3 or below -0.3 in both datasets) are shown in (b, c, d) and the rest are shown in (e, f, g).