Supplementary Figure 4: Mbd1−/− mice have normal thymocyte populations. | Nature Immunology

Supplementary Figure 4: Mbd1−/− mice have normal thymocyte populations.

From: The transcriptional regulator Aire coopts the repressive ATF7ip-MBD1 complex for the induction of immunotolerance

Supplementary Figure 4

(a) Representative FACS plots of CD4 and CD8 thymocytes from 4 month old Mbd1+/+ and Mbd1−/− mice. Numbers represent the percentage of cells in each gate. (b) Representative FACS plots of thymic Tregs (CD4+/CD25+/Foxp3+) from 4month old Mbd1+/+ and Mbd1−/− mice. Numbers represent the percentage of cells in each gate. (c) Graphs show the percentage of CD4, CD8, double positive (DP), and thymic Tregs from three mice of each genotype. NS = not statistically different. Each circle or square represents one mouse.

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