Supplementary Figure 1: TNFRSF expression during thymocyte development. | Nature Immunology

Supplementary Figure 1: TNFRSF expression during thymocyte development.

From: Costimulation via the tumor-necrosis factor receptor superfamily couples TCR signal strength to the thymic differentiation of regulatory T cells

Supplementary Figure 1

Thymocytes from Foxp3-GFP reporter mice were harvested and evaluated by flow cytometry for expression of GITR, OX40, TNFR2, and CD27. Gates used to identify the indicated populations were as follows; DN thymocytes: CD4−CD8− (grad shaded histograms), DP thymocytes: CD4+CD8+ (black lines), conventional CD4SP: CD4+CD8−CD25−Foxp3− (red lines), Treg cell progenitors were CD25+Foxp3− (green lines), and mature Treg cells were CD25+Foxp3+ (blue lines).

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